1. 个人简介:
宁聪琴博士,研究员,材料学专业硕士/博士生导师
邮箱:cqning@shnu.edu.cn
教育经历:
1997-2001,博士,哈尔滨工业大学
1995-1997,硕士,哈尔滨工业大学
1991-1995,学士,哈尔滨工业大学
工作经历:
2020-至今,澳门沙金在线平台 研究员
2006-2020,中国科学院上海硅酸盐研究所副研究员/研究员
2003-2006,美国肯塔基大学,博士后
2001-2003,上海第二医科大学附属第九人民医院,博士后
2. 主要研究方向:
[1] 可降解生物活性骨修复材料
[2] 新型有机/无机齿科修复材料
3. 代表性科研项目:
[1] 烧结助剂对新型硅磷酸钙生物陶瓷的性能调控与作用机理研究,2017-2020。
[2]先进硅磷酸钙基骨修复材料,中国科学院国际合作项目(中奥),2020-2021
[3]硅磷酸钙、二氧化硅纳米微粒合成工程化技术研发,国家重点研发专项,2017-2020
[4]牙科修复用复合陶瓷工程化样品的开发研究,上海市科委生物医药支撑项目,2017-2020
[5] 新型硅磷酸钙材料生物活性机理的蛋白质组学研究,中国科学院国际合作重点项目,2017-2019
[6]骨组织工程用磷酸钙/氧化硅生物活性陶瓷材料的制备与表征,(2007-2009)
4. 代表性论文及著作:
[1]C. Q. Ning*. Biomaterials for Bone Tissue Engineering. In Biomechanics and Biomaterials in Orthopedics (2nd Edition).Edited by D.G. Poitout. Springer-Verlag London, SURREY, ENGLAND.2016: 35-57.
[2]K. R. Dai*, C.Q. Ning.Shape memory alloys and their medical application. In Biomechanics and Biomaterials in Orthopedics(2nd Edition).Edited by D.G. Poitout. Springer-Verlag London, SURREY, ENGLAND. 2016: 187-195.
[3]W. Su, J. S. Guo, J. J. Xu, K. Huang, J. B. Chen, J. Jiang, G. M. Xie, J. Z. Zhao*, S. Zhao*, C. Q. Ning*. Gradient Composite Film with Calcium Phosphate Silicate for Improved Tendon–to-Bone Intergration.Chemical Engineering Journal. 2020, 404: 126473.
[4]F. Y. Deng, W. Y. Zhai, C. Q. Ning*.Advanced protein adsorption properties of a novel silicate-based bioceramic: a proteomic analysis.Bioactive materials. 2021, 6: 208-218.
[5]F. Y. Deng, J. C. Rao, C. Q. Ning*. Ferric oxide: A favorable additive to balance mechanical strength and biological activity of silicocarnotite bioceramic.Journal of the Mechanical Behavior of Biomedical Materials. 2020, 109: 103819.
[6]J. K. Zeng, J. S Guo, Z. Y. Sun, F. Y. Deng, C. Q. Ning*, Y. Z. Xie*. Osteoblastic and anti-osteoclastic activities of strontium-substituted silicocarnotite ceramics: in vitro and in vivo studies. Bioactive Materials. 2020, 5: 435-446.
[7]S. X. Xu, Q. Wu, J. Wu, H. M. Kou, Y. J. Zhu, C. Q. Ning*, K. R. Dai. Ultrasound-assisted synthesis of nanocrystallized silicocarnotite biomaterial with improved sinterability and osteogenic activity. Journal of Materials Chemistry B. 2020,8(15): 3092-3103.
[8]J. S. Guo, K. Li, C. Q. Ning*, X. Y. Liu*. Improved cellular bioactivity by heparin immobilization on polycarbonate film via an aminolysis modification for potential tendon repair. International Journal of Biological Macromolecules. 2020, 142: 835-845.
[9]S. X. Xu, H. M. Kou*, Y. P. Guo, C. Q. Ning*. Highly dense Ca5(PO4)2SiO4 bioceramics with ultrafine microstructure prepared by pressureless sintering. Ceramics International. 2019,45: 23728-23733.
[10]F. Wang, J. S. Guo, K. Li, J. Sun, Y. P. Zeng, C. Q. Ning*. High strength polymer/silicon nitride composites for dental restorations. Dental Materials. 2019, 35(9): 1254-1263.
[11]J. S. Guo, S. Wei, J. Jia, C. Q. Ning*, J. Z. Zhao*, X. Y. Liu*. Enhanced tendon to bone healing in rotator cuff tear by PLLA/CPS composite films prepared by a simple melt-pressing method: an in vitro and in vivo study. Composites Part B: Engineering. 2019, 165: 526-536.
[12]F. Y. Deng, F. Wang, Z. W. Liu, H. M. Kou, G. F. Cheng, C. Q. Ning*. Enhanced mechanical property of Ca5(PO4)2SiO4 bioceramic by a biocompatible sintering aid of zinc oxide. Ceramics International. 2018, 44: 18352-18362.
[13]J. S. Guo, C. Q. Ning*, X. Y. Liu. Bioactive calcium phosphate silicate ceramic surface-modified PLGA for tendon-to-bone healing. Colloids and Surfaces B: Biointerfaces. 2018, 164: 388-395.
[14]F. Wang, Y. Y. Xiong, C. Q. Ning*, J. Sun, Y. P. Zeng. Effects of pore connectivity and microstructure on mechanical performance of ZrO2 scaffolds and PMMA-infiltrated ZrO2 composites. Journal of Alloys and Compounds. 2017, 728: 189-195.
[15]S. Zhao, L. J. Peng, G. M. Xie, D. F. Li, J. Z. Zhao, C. Q. Ning*. Effect of the Interposition of Calcium Phosphate Materials on Tendon-Bone Healing During Repair of Chronic Rotator Cuff Tear. American Journal of Sports Medicine. 2014, 42(8): 1920-1929.
[16]W. Duan, C. Q. Ning*, T. T. Tang. Cytocompatibility and osteogenic activity of a novel calcium phosphate silicate bioceramic: Silicocarnotite. Journal of Biomedical Materials Research Part A. 2013, 101A (7): 1955-1961.
[17]Y. P. Guo, Y. B. Yao, Y. J. Guo, C. Q. Ning*. Hydrothermal fabrication of mesoporous carbonated hydroxyapatite microspheres for a drug delivery system. Microporous and Mesoporous Materials. 2012, 155: 245-251.
[18]W. H. Lu, W. Duan, Y. P. Guo,C. Q. Ning*.Mechanical Properties and in Vitro Bioactivity of Ca5(PO4)2SiO4 Bioceramic. Journal of Biomaterials Applications. 2012, 26: 637-650.
[19]Y. P. Guo, L. H. Guo, Y. B. Yao,C. Q. Ning*, Y. J. Guo. Magnetic mesoporous carbonated hydroxyapatite microspheres with hierarchical nanostructure for drug delivery systems. Chemical Communications. 2011, 47,12215-12217.
[20]C. Q. Ning*, D. Y. Ding, K. R. Dai, W. Y. Zhai, L. Chen. The effect of Zr content on the microstructure, mechanical properties and cell attachment of Ti–35Nb–xZr alloys. Biomedical Materials. 2010, 5(4): 045006.
[21]D.Y. Ding, C. Q. Ning*, L. Huang, F. C. Jin, Y. Q. Hao, S. Bai, Y. Li, M. Li, D. L. Mao. Anodic fabrication and bioactivity of Nb-doped TiO2 nanotubes. Nanotechnology. 2009, 20: 305103 (6pp).
[22]C. Q. Ning, Y. Zhou. Correlations between the in vitro and in vivo bioactivity of the Ti/HA composites fabricated by powder metallurgy method. ActaBiomaterialia. 2008, 4: 1944-1952.
[23]C. Q. Ning*, J. Mehta, A. El-Ghannam. Effects of Silica on the Bioactivity of Calcium Phosphate Composites in vitro.Journal of Materials Science: Materials in Medicine. 2005, 16 (4): 355-360.
[24]C. Q. Ning*, Y. Greish, A. El-Ghannam.Crystallization behavior of silica-calcium phosphate biocomposites: XRD and FTIR studies. Journal of Materials Science: Materials in Medicine. 2004, 15 (11): 1227-1235.
[25]C. Q. Ning*, Y. Zhou. On the microstructure of biocomposites sintered from Ti, HA and bioactive glass. Biomaterials. 2004, 25: 3379-3387.
[26]C. Q. Ning*, Y. Zhou. In vitro bioactivity of a biocomposite fabricated from HA and Ti powders by powder metallurgy method. Biomaterials. 2002, 23: 2909-2915.
[27]宁聪琴*,戴尅戎, 汤亭亭. 硬组织替换用羟基磷灰石复合材料的研究进展.生物医学工程学杂志, 2003, 20: 550-554.
[28]宁聪琴*, 周玉. 医用钛合金的发展与研究现状.材料科学与工艺, 2002, 10(1): 100-106.
5. 学术兼职与荣誉:
美国陶瓷学会旗下International Journal of Applied Ceramic Technology副主编
Journal of Biomaterials and Tissue Engineering编委
中国生物材料学会植入材料与器械专委会委员
中国硅酸盐学会特种陶瓷分会第九届理事会理事
中国专利审查技术专家(JSZJ0969)
上海市女科学家联谊会第八届理事会理事
上海市科技党委三八红旗集体(2014年)
上海市巾帼文明岗(2015年)
6. 代表性授权及申请专利:
宁聪琴,赵迎珂,常江,硅酸钠钙(Na2CaSiO4)生物材料的制备方法及其用途,专利号:ZL200810200172.8
宁聪琴,鲁文豪,硅磷酸钙生物材料及其制备方法和用途,专利号:ZL201010202227.6
宁聪琴,鲁文豪,硅磷酸钙生物材料及其制备方法和用途,专利号:ZL201310046949.0
宁聪琴,鲁文豪,硅磷酸钙生物材料及其制备方法和用途,专利号:ZL201310046999.9
宁聪琴,袁萍, 具有药物缓释作用的有机/无机复合三维多孔支架及其制备方法,专利号:ZL201310116098.2
王锋,宁聪琴,一种复合陶瓷材料及其制造方法和应用,专利号:ZL201710071165.1
王锋,宁聪琴,曾宇平,一种氮化硅-树脂双连续相复合陶瓷材料及其制造方法和应用,专利号:ZL201710228918.5
邓繁艳,宁聪琴,一种兼具力学强度和降解性的生物活性陶瓷材料及其制备方法,专利申请号:201810175064.3
宁聪琴,郭劲书,赵金忠,苏为,一种梯度复合材料及其制备方法和应用,专利号:ZL201810584325.7
宁聪琴,许顺祥,寇华敏,一种硅磷酸钙纳米粉体、制备方法和应用,专利申请号:2018114592417
宁聪琴,刘晓丹,寇华敏,一种超细硅磷酸钙粉体的水热法制备及其应用,专利申请号:2018114567364
宁聪琴,李可,一种高强度二硅酸锂玻璃陶瓷及其制备方法和应用,专利申请号:2019111725445